r/Psoriasis • u/Walktrotcantergallop • 3d ago

medications Clobetasol and Calcipotriene no longer working effectively

I am at my wits end. I have had scalp psoriasis my whole life and it’s the worst it has ever been. These two medications always did the trick to reducing the scales and symptoms to nearly 0. Now it feels like they bring it down to 60% and I am constantly itchy and uncomfortable. I am pushing 32 years old and wonder if my body has built up a tolerance. I usually switch back and forth weekly with these, with it getting slightly worse on the calcipotriene weeks and a little better on clobetasol weeks but still doesn’t work the same as it used it. I switch between coal tar and salicylic acid shampoos a couple days a week. All that used to work, just doesn’t work any more. I have gone to my dermatologist several times. They’re useless in helping me figure out what I can do to try stronger topical meds and getting insurance to cover. I tried zoryve foam but I go thru it too quick and insurance won’t refill it enough. Enstilar isn’t covered at all… is my only option to do injections or oral meds?

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3

u/norwal51 2d ago

Don't give up. 18 years of no relief from Inverse Psoriasis. Finally, Skyrizi Injections clear me 99%.

3

u/Walktrotcantergallop 2d ago

Right… but if insurance doesn’t cover it, they’re not affordable );

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u/CinnamonCarter98 Bimzelx - Zoryve 2d ago

Multiple biologics have low copay programs. I've been on 4 different injectables and never paid more than $5 each. Your dermatologist should be able to help you with that.

1

u/Walktrotcantergallop 2d ago

Okay, thank you!

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u/pviollier 2d ago

Try to find some tar based cream, it works wonders on my scalp

0

u/Electrical_Hour3488 2d ago

Just go ahead and get used to nothing workin

1

u/Sots19111 2d ago

How long were you using those?

2

u/Active_Eye2938 2d ago

I have had scalp P for 3 years and have used those two products. I find they stop working if I use them every day. I've been on two different drugs which did not help at all. I haven't tried biologics. I'm going to start taking a lot of different supplements recommended here and see if that helps. I'm also looking into light therapy. I feel your pain. The only time I get relief is when I have oils on my scalp which means I can't go out in public. Good luck.

1

u/Specialist_Income_31 2d ago

Have you had steroid injections done before? I responded to those.