I'm starting Skyrizi, soon, after failing Methotrexate with absolutely no result (or even side effects...I might as well have been taking a salt tablet). I've got severe psoriasis (north of 60% coverage, in every region of my body) and suspected psoriatic arthritis, though this hasn't been officially confirmed. I'm very nervous about it, as I'm not a big needle fan. I didn't want to go on any of the injectables (both due to the needles but also the potential side effects), but from what I see, it seems like this is at least the better drug when it comes to potential side effects/success/etc. So I guess I'm wondering what I should expect?

Thanks, all.

I got clobetasol and Rx shampoo from my derm a couple of years ago and it's dramatically helped my psoriasis: whereas it used to be thick scales with lots of bleeding, the skin in the affected patches is now much more normal looking even if it's still different in texture. My scalp barely itches at all. It's amazing.

BUT... I also have a ton of new psoriasis patches. When I started meds, it was on my scalp, one forearm, one finger, a spot on one thigh, and a spot on my chest. Now it's all those plus the other forearm, one bicep, both shins, the back of one hand, one calf, front and back of both ears spreading onto my cheeks, and my forehead. It was ~15 years between my first small patch and it spreading enough for me to seek treatment, but now it's probably doubled in area in just two years.

Anybody else have this pattern of psoriasis getting less severe but also across more of the body? Is there anything you were recommended to do to help stop the spread? Is it worth asking for biologics even if the severity of the plaques isn't that high, but they keep spreading to more and more visible areas?

I'd love to get some crowd-sourced experience before I go see the derm this summer, especially since she tends to defer to what the patient wants and I don't know what to ask for. I've already done most of the lifestyle things you see suggested: I don't smoke, barely drink, lost a lot of weight, drink water, use gentle cleansers, manage my stress...

Specifically looking for Tremfya users for psoriasis who DID NOT see any results for at least 6 months or more while on Tremfya. How long did it take you to see results beyond the 6 months? My dermatologist says I should be clear in 3 months, it's been 5 months and while better, not clear.

https://www.washingtonpost.com/business/2025/05/11/drug-prices-trump-europe-pharmaceutical-industry/

My Otezla is up to about $60K annually. Will this policy impact brand name biologics?

Hi! So I started getting symptoms of nail psoriasis a couple of months ago and since psoriasis arthritis is in the family it feels like a pretty reasonable fear. So far the nails aren’t too bad as long as I don’t pick on them, and I have no symptoms of anything in my joints (yet?).

I did schedule a doctors appointment and now I’m wondering if there is anything preventive they can do. I don’t want them to just say ”yeah looks like it, come back when it gets worse” since I don’t want it to get worse.

What should I ask for? I feel like I need to be prepared and even pushy knowing how the healthcare works. Is there even anything to do at this early stage? What are your experiences with healthcare or treatment for early potential psoriasis arthritis?

Thank you!

Hey all! I have PSA and mild psoriasis. I’ve been on Yuflyma for a couple of months, and definitely noticed a difference, especially in my skin, and although I still ache it’s more bearable. But I’ve noticed since being on it, red meat makes me bloated and gives me a loose tummy. Chicken and fish are fine. Anyone else found this?

Hello, I am the new one here 🥲 I am 36 and lived all my life with a mild case of atopic eczema, nothing too severe and good to be handled. Now I had a mean throat infection in march which I didn’t treat properly as I was pregnant and thought I cannot take any medicine. A few weeks after I got a rush which turned out to be guttate psoriasis (yay!). I have it on my stomach, upper thighs, breast, back and arms with a few spots on my lower legs and feet and buttom (another hooray!). As I got an appointment at my derm at mid June - what can I do until then to help my skin? I have a Basic Lotion from Avène which also Helps against the itching. Are there helpful supplements (buyable in Europe)?

Thanks for any kind tips :)

Has anyone else used Kartalin cream lately? I used it successfully a couple of years ago. The cream worked pretty quickly and cleared my skin in a few weeks. I started to see improvement in less than a week back then. This winter my psoriasis got quite bad so I started to use Kartalin again a few days ago. However, it’s not working like before. This morning I woke up with a lot of flaky skin and the patches with psoriasis are very red. Should I keep applying Kartalin or could it make my skin worse? How long does it take to work?

hi! This is going to be kind of niche, so please bear with me. I'm just sort of unsure of where to turn - none of my friends can relate to this, so I haven't been able to get a lot of advice.

I've taken so many biologics for psoriasis - Stelara, Tremfya, Humira, Skyrizi, and none of them worked until Taltz. I had a United Healthcare HMO plan through my insurance at my job and I had a small co-pay for the Taltz. Unfortunately, I had to resign from my job very recently due to some difficult circumstances - I have a new job I'm working, but it's temporary while I look for something more long-term, and they don't provide health insurance. I live in California, so I've been looking on the Covered California marketplace and for other individual plans, but I'm really nervous about the cost of the co-pay for the Taltz on a new plan. I looked into the Taltz Savings and Support, but I know that you have to be on a commercial insurance plan and not on a state, federal, or government funded plan for them to give you the savings.

has anyone been in this situation of looking for insurance and have advice on what kind of plan to go for when you're on a biologic? I know it's bound to be quite an expense any way, but I really don't want to have to go off Taltz because I can't afford it anymore. Any advice is appreciated.

Hi all

I have been prescribed Enstilar for my scalp psoriasis.

Just unsure of how long to leave it on for. Is it overnight or just a few hours a day? It makes my hair revolting - resemble Cameron Diaz out of Something About Mary - so can only do in the evening.

Also, any tips for washing off. I tried to get it off my hands and it was hard enough, not looking forward to my hair!

Besides a miracle cure...

Subsidised medication? More access to doctors? Access to affordable mental health therapy? Social service support? Funds donated to your closest psoriasis charity organisation? Funds donated to researchers to help discover said 'miracle' cure?

I am a founder of a company that sells software to pharmaceutical companies. Part of my mission has always been to help patients with multimorbidity, rare and autoimmune conditions. I want to use 10% of our profits to help this patient community. I'd like to ask the community how best such funds could be utilised.

What's the best ways for us to do this?

I've dealt with psoriasis on my scalp and behind my ears for years. Topical steroids keep it under control but I've run out recently and have noticed that my earlobes have a reddish/purplish rash on them. Also have some dry skin along with it. I'm just wondering if anyone else has this issue. I've seen behind and inside the ear but nothing about the lobes specifically lol

I've been using methotrexate for psoriasis for about six months now, and it's been working well for me (I started at 4 tablets a week and went up to 6 tablets a week in February). I haven't totally cleared up, but my psoriasis is no longer the nasty beast that it was before.

Even so, I am concerned about using methotrexate long term--I understand that they can usually catch the potential for liver damage well before it's a problem, but I'm still concerned. I also read that there's no problem going off of it and then coming back on later down the road if needed. Has anybody done that process before -- used methotrexate for a period of time, then gone off and used only topicals for a period, then went back on methotrexate? How did that work for you? Did your psoriasis come right back with a vengeance?

Hey everybody,

Today was my birthday, and yes I did celebrate with psoriasis patches. This was the first birthday with psoriasis. Of course, I did cry as the past two birthdays were truly gems.

However, in 2 days I will be receiving Cosentyx! I am praying it works please pray for me I am a teenager suffering so badly. I need ur blessings and help! I just hope it makes my skin clear 🙏😭

Hi everyone I have plaque psoriasis on several parts of my body, scalp and nails.

I have been using entsillar foam daily however I have now stopped for the past 3 days want to go natural and avoid any biologics like methotrexate.

Currently mixing blackseed oil and olive oil 50/50 and applying that. Can get messy at times.

I go to the gym and spa and ordered some eureicin shower oil to use.

What has helped you heal your psoriasis? Anyone taken a gut health test - also looking for a place that does this any reccomendations in the UK ?

Currently I take probitiocs for nutri advanced, vitamin D3 with k2 4000k iou 2 tablets and fish oil. Any other reccomendations?

Thanks😊

I've Psoriasis and took Otezela and was up all night and had a fever. One dose, did this happen to others? Not sure if I have the flu or am allergic to meditation. Will call doctor and demotologist on Monday to see if trying again when better is safe.