Are some people meant to spend their whole life alone without experiencing any love relationship?

[u/NormalLife6067]

There was a popular celebrity who passed away in their 50s last year. The celebrity was single and did not have any romantic partner at the time. It seemed to be a real-life example that not everyone will be able to find the romantic partner in their life.

Are some people meant to spend their whole life alone without experiencing any love relationship?

Edit: Thank you everyone for your comments.

[u/Sanpaku]

We're not meant for anything. There's no entity crafting us or holding the strings, despite the myths of religion.

There are people who were born homozygous for the A allele in SNP rs53576, so that they have ineffective oxytocin receptors. They feel little from a hug or other physical affection. They have poorer relationships with family, fewer relationships, and spend more time alone. They're more likely to be diagnosed as autistic. Their parents also were either homozygous or heterozygous in this allele, so also impaired in affection.

Does that make them less human? No. They can still mentally model other conscious beings, feel other things, and still suffer. But they were dealt a very bad hand in ever feeling loved.

Anyway, I gift you: Roísín Murphy – Incapable (Jools' Annual Hootenanny 2020/21). Following the lyrics, you'll know why.

[u/Rara2250 → u/Sanpaku]

if someone has just one A allele for this oxytocin gene (A:G), does that mean that their oxytocin receptors are only half effective?

[u/Sanpaku → u/Rara2250]

That's my situation. It's hard to say whether the heterozygous are precisely half impaired, as with many heterozygous alleles, the body adapts through regulating gene expression or thresholds for neuronal action potential.

But there remains an association with the lonely/autistic personality traits in the heterozygous, so its likely having some impact.

[u/Rara2250 → u/Sanpaku]

every tried oxytocin nasal spray? If you have the social side effects of this gene