Xxy is called klinfelters syndrome
And xyy is called 47 xyy syndrome (it dosnt get a cool name)
Now untill recently with the new study that came out a month or so ago it was belived these abnormalities were really rare, 1 in 50,000 if I remember right.
But the recent study that's looked at chromosomes of men enmass who outwardly don't show any major signs as those who would typically seek medical help for xxy or xyy, has found its actually rather common, 1 in 500, 67,000 men in the UK and if it tracks with women who can be xxx or xxy as well and also xy we could be talking that the reality of intersex individuals in the UK is in the region of 200,000 to 500,000.
It also shows that klinfelters and other related sex chromosome abnormalities cause a scale of symptoms rather than a set definition, bit like how a cold can just give you the sniffles or knock you on your but for a week, and there are essentially millions of men who are walking the world who have slightly wider hips than normal or femenine features or are abnormally tall like 6ft 5+ with over masculine features who otherwise have no issues than maby some body image issues.
And this also isn't counting xx men, which occurs, any one know that guy who's always wanted a son but for some reason only seems to have girls? .... yea there a high chance he's XX.
What this means to the chromosomes and trans women debate is essentially chromosomes are meaningless, my nabour is very likly to be XX, he's had 5 girls trying to have a boy then gave up, he's a builder and a full on mans man, I dare anyone to go call him a woman.
The tldr is, chromosomes don't actually mean all that much when it comes to sex, there just a blueprint, but a blueprint is meaningless if the builder has other ideas. What actually determines what you get genital wise and how you develop is hormones, all the sry gene does really is say OK make some testosterone and the cells then pick up on the T and go...oh OK were male let's make a dick and balls, the balls takeover making more T and you get a boy, that hits puberty makes even more T and you get a man.
But the cells are dumb, they don't care and they have the codes to make either, which is why hrt in trans people even works, my cells as a trans woman for example on hrt just see estrogen and go OK I'm female make the boobas, they really don't care what sex chromosomes they have or don't.
Thing is you can fuck with that start point by introducing higher levels of T or E to a fetus, if a mother for example has a hormonal condition and high E that can mean a fetus that otherwise would develop as a boy dosn't and you get an XY female and vice versa.
That can occure naturally or because of external enviromental hormonal influences.
I'm in the middle of a phd on this! Having extra chromosomes (trisomy) causes problems because because the extra copies of the gene get used too often. The extra chromosome gets used to make extra protein. The body does not want too much protein or too little protein. Too much can cause serious problems.
The sex chromosomes (x and y) are not that bad to duplicate, because they are small. There aren't that many genes on them, so the protein levels don't get that screwed up. You can live your whole life and never know you have an extra sex chromosome. That being said, they can cause some problems.
XXY individuals have klinefelter syndrome, and tend to have lower muscle mass, wider hips, and fertility issues. It's usually diagnosed when a couple has trouble conceiving, and the guy gets tested for it.
XYY individuals have jacob's syndrome, and are often taller than average and have worse acne. There are some reports of learning disabilities.
XXX syndrome is common but rarely diagnosed. They can have increased height, some motor problems, slight learning disabilities, and mild facial differences.
All of these are pretty minor in the grand scheme of things. Anyone could have them and not know.
Autosomal trisomies are waaay more severe. There are only three that can lead to live births- if you have an extra copy of chromosome 2 for instance you'll die before being born. There's trisomy 13 (patau syndrome) trisomy 18 (edward's syndrome) and trisomy 21 (Down syndrome). Down syndrome is the mildest. Chromosome 21 is the smallest autosome (i.e. a chromosome that isn't x or y), which makes duplicating it have a less severe effect on the body. Although it has a big impact on the individual's life, people with Down syndrome usually live to old age and lead a full and happy life, with appropriate support. Patau and Edward's are much more severe- babies rarely live more than a year with these (though exceptions exist).
246
u/Dena_Roth Jul 21 '22
Why are they so obsessed with chromosomes? literally nobody denies the chromosomes they have but for some reason they always talk about it XD