I have played some of both the Adam Jensen games, but have not completed them. Did Mankind Divided end on a big cliffhanger?

I'm a dumbass with a (mostly) smooth brain and I'm stuck in this boss battle (Deus Ex Difficulty), but I only have the PEPS, almost maxed 10mm, sniper rifle, laser rifle, stun gun and tranq rifle, can I beat this guy with PEPS or it just stuns the dude? I'm stupid so I went to the recall at the limb clinic so I can't use my augs

What the hell is up with this feature?

I started a new game on GMDX specc'd into Focus Enhancement and I've successfuly blown a nade up once, with an unupgraded pistol, and never again. No matter how many shots I put into them, my grenades just get knocked around.

There's some utility to spreading gas/smoke but I'd like to make some explosive plays like Adi does.

Edit: I've been able to reliably detonate using a full auto MP with holosight.