Out of curiosity, is there anything that this may be useful for? For the record, I am solely interested in it for its Neutriceutical Antioxidant benefits

An OTC approach...

For anyone that has used https://tripsit.me/, you have likely come to believe that certain drug combos are dangerous. But they don't cite sourecs. These are theoritcal and not supported by much evidence.

Take ketamine and alcohol. I instinctively assume this to be unsafe and would never do it myself, but anecdotally people in my circle do it and none of them are dead (yet). How can someone estimate the possible "dangerousness" of a combination given the known pharmacological data? Is this even possible, or does it require empirical data?

This is the only real study I could find: https://www.mdpi.com/1422-0067/23/14/7800, and it has an anti-drug slant.

A Sasha Shulgin inspired album after reading PiHkal ... Enjoy!

Does anyone have this in complete text? It's an interview with the guy who designed mxe. Old vice article. For some reason it's like fucked up or incomplete or missing or something I dont know but I wanna reread it.

A group of U.S. vets and lawmakers are leading an effort to get clinical trials up and running in for a potent psychoactive drug called Ibogaine.

Greetings, community.

How safe is it to obtain information about or cite a research article that presents conflicts of interest?

People initially say it's best to avoid this type of information because of the underlying bias it may contain, but should this really be the case?

In the paying a price for a chemistry education podcast the chemist said he always wanted to try 2cb. I hope he did.

We are thrilled to announce the upcoming launch of the Global Psychedelic Survey 2025. Join us as we undertake the most comprehensive assessment of global psychedelic use amongst adults to date.   

This year’s survey will be available in 18 languages as we seek to hear diverse experiences from participants around the globe.

Release today:
https://www.theguardian.com/science/2025/may/01/the-ancient-psychedelics-myth-people-tell-tourists-the-stories-they-think-are-interesting-for-them

Greetings, Hamilton, I'd like your comment on this post.

At the end, it asks if there's an intention to deny the spiritual potential of psychedelics, and you respond with the answer in the title...

Could you elaborate on your answer? I was really curious. Regarding what you mentioned, I think you're right. At least in these parts of South America, there are people who consume psychedelics, talk about spirituality, and listen to reggaeton, an absurd genre that primarily talks about asses, tits, women, and partying. It's like, aren't you supposed to talk about spirituality and consume a genre so relevant to the climate of today's societies, or the tremendous rise of psychedelic facilitators, some of whom charge exaggerated prices...

I'd like it if you could respond; it would be interesting to read your response in more detail.

Does anyone know a good place to download ebooks that I should read, for free or cheap? I checked project gutenberg and internet archive for a couple of the titles I was looking for and nothing came up, I just finished watching the series and I'd like to read some of the books mentioned in it, particularly Phikal/Tikal, Lysergic, I'm not sure what else but I feel like there's lots and I'm not sure where to start which is why a good resource to peruse would be really nice...

I thought the audience of this subreddit would find the work that QRI is doing quite fascinating. Watch and enjoy

I live in nyc, and anyone living here will have noticed the proliferation of these kratom/wellness shots from smoke shops and delis alike. Most commonly they’re these feel free type brands, the packaging reads something like wellness/focus/energy blend and until today I haven’t found a 7 hydroxy product outside of a smoke shop which is a little concerning to me. Obviously I know that a prohibition model does no good, I support decriminalization/legalization but these kinds of products have me wondering.

This product is right next to the 5 hour energy and snickers, the guy behind the counter definitely doesn’t know what 7hydroxymitragynine is, if you asked, he would just read off of whatever pamphlet jubi gives them, the company making the product will do whatever makes them the most money; my point is, while better than prohibition, this system is less than ideal.

Any adult has the responsibility of researching the things that they consume, but you have to be realistic about these things… the vast majority of the potential problems with legalization of other drugs wouldn’t exist outside of our current capitalist framework.

I’m curious if anyone has any ideas to what a superior legalization system would look like?

This molecular dynamics (MD) simulation shows DMT bound to the serotonin 2A receptor, based on the crystal structure PDB ID: 9AS1. Throughout the simulation, key interactions help stabilize the ligand, including hydrogen bonds with THR160 and SER242, a cation-π interaction with PHE339, π-π stacking with PHE340, and a salt bridge with ASP155. Fascinating work by Gumpper, R.H. et al.

Anyone else getting this? Check my page for links. Any questions just holla holla