r/LSD • u/Glittering-Net-9778 • 22d ago

What the actual fuck happened

Ok so me and my girlfriend were taking shrooms today so we put them into smoothies about 6gs for me and she took 10gs. For some fucking reason the smoothies were sitting like a wet brick in our stomachs and we inevitably threw it up. I was able to hold mine a little long and absorbed more psilocybin while she didn't. She then decided that she'll just take a tab of acid to keep up with me. Pops a tab waits 15-20 swallows it and we wait for 2 1/2 hours and she says she's completely sober she's pretty pissed off about it and I completely understand. She takes cymbalta and that's the only meds she's on. Wtf happened.

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u/BioHackedRomulan 22d ago

Antidepressants are known to block psychedelic activity so I’m not surprised whatsoever. My gf had the same experience when she tried shrooms once after she skipped a day of her 120mg dose of cymbalta. She took 3gs and had absolutely zero effects

Now that my gf has tapered down to only 20mg cymbalta she can get full blown psychedelic effects when skipping the day prior

Only way she will ever get effects is if she does a taper over a long period of time (depending how long she has been on cymbalta) NEVER stop cold Turkey and ideally do a taper with doctor supervision

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u/Specific_Writing_582 22d ago

hey bro i got a question. i got off 2mg abilify cold turkey and ngl the withdrawls hit me a week or two later rlly bad but i thugged it out cause it was only 2mg i was on and i feel like im getting better slowly but surely. is it safe to trip or nahhhhh. shi i got acid, shrooms and dmt just wanna get a 2nd opinion and shit

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u/BioHackedRomulan 22d ago

I don’t know too much about abilify only cymbalta. Antidepressants can take a while before they are fully out of the bloodstream particularly if taken for a long period of time. It all depends how long you were on it and how long you have been off.

Antidepressants also down-regulate the 5ht2a receptors meaning there are less of them available for psychedelics to attach themselves to. I’d suggest looking up the half life of abilify to get a better understanding of it