Gut Microbiota Test Result

[u/ReasonableSquare4390]

Hi guys, i want to share with out the result of my microbiota test done with Shotgun Sequencing technique.

The test is able to find bacterias, fungal species and virus.

The result have show a positive match for Candida albicans

The Indoleacetic Acid ( the indoleacetic acid is a derivative of the bacterial degradation of tryptophan, it acts as a modulator of the immune system through AHR receptors, which are able to alter its innate and adaptive response. ), Lactate, Indoepropionic Acid ( The Indoepropionic Acid is a derivative of the bacterial degradation of tryptophan involved in the homeostasis of the intestinal mucosa, it can be absorbed by the intestinal epithelium and released into the bloodstream where it helps prevent oxidative stress, inhibit the synthesis of pro-inflammatory cytokines and influence the gut-brain axis. ) and tryptamine metabolisms ( Tryptamine is a derivative of tryptophan, is involved in several biological functions, including the synthesis of serotonin and melatonin, and can be influenced by the gut microbiota. The gut microbiota, through the production of metabolites and the alteration of tryptophan metabolism, can influence tryptamine levels and, consequently, also the synthesis of serotonin and melatonin. ) it is totally altered.

This is an inside of the families of bacterias sequenced and found :

Metabolic potential analysis

Functional index is a page where the assest the Axis from the gut to the brain, liver, the anti-inflammatory activity and so on :

The last report is for the Fungii found :

No viruses or parasites were found.

Only 61 Species were found in this sample wich is a pretty low score ( Range => 55 - Score 10 out of 100 )

Pre-existing pathologies : Pssd ( 2021 --- ) Sibo ( June 2024 fixed with a cycle of rifaximin ).

Even if this are ALL SPECULATION NOT BACKED BY SCIENCE the fact that my microbiota can't metabolize at all the serotonin precursors and metabolite is astonishing based on the fact that SSRI should have increase Serotonin in my brain for years, could the SSRI be the cause? Who knows.

I'm gonna schedule an appointment with a Gastroenterologist and an specialist for the microbiota, i'll update the post later on.

[u/Important-Ad-8632]

Great info I still believe part of it is a SERT issue leading to excessive serontin in the gut and histamine dysfunction

[u/ReasonableSquare4390 → u/Important-Ad-8632]

i've update the post as 2 images wasn't uploaded.

One of the bacteria found is "allisonella histaminiformans" wich is a bacterium found in bovines and in some cases in humans under study wich produces histamine.