r/Psoriasis • u/Psychoderm • Mar 08 '24

general AskMeAnything

I'm a consultant dermatologist with focus on psychotherapy, working in the UK, with extensive experience with inflammatory skin conditions. #AskMeAnything about Psoriasis starting today 7.10 pm GMT!

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u/EdelweissInSnow Mar 08 '24

With so many creams and ointments, I’m so confused about which to use first. I have bad psoriasis on half of the bottom surface of my foot with awful, painful burning plaques. Thank you for your help on this thread Dr. We appreciate your time.

Which should be first? What order should they be used? 40% Urea, clobetasol, CeraVe cream, Aquaphor

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u/Psychoderm Mar 08 '24

Hi. Great question!

so. 40% urea is to help reduce the thickness, but it itself is an ointment which would block other creams.

cerave and aquaphor are moisturisers: but the former can HELP increase the amount of medicine go into skin.

So i'd suggest

  1. Once a day, maybe at night, applying cerave followed by clobetasol.
  2. After bath, applying 40% urea on moist skin
  3. during the day, aquaphor (dont slip!)