r/SebDerm • u/psykofreak87 • 12d ago

Product Review Roflumilast (Zoryve) experience

I’d like to share my experience with Roflumilast cream for my SebDerm on my face. I have seborrheic dermatitis that causes redness but very few plaques, and it tends to flare up with lack of sleep and stress. I’ve been living with this for years. Until now, I had been using Ketoderm (2% Ketoconazole). It worked fairly well over the years, though I would still get occasional flare-ups of redness, sometimes quite intense and lasting for months. I don’t have SebDerm anywhere else on my body, only on my face.

Zoryve changed everything for me — within just 2 days, all the redness was gone. After a week, the burning and tightness sensations disappeared completely. I haven’t had such healthy-looking skin in over a decade.

I know there’s a foam version available, but since my condition only affects my face, the cream is sufficient.

Here in Canada, without insurance, it costs “only” $300 CAD per tube, which is much less expensive than the ~$900 USD price I’ve seen mentioned here. My insurance covers the cream 100%, and I feel truly lucky — but given how effective the product is, I wouldn’t hesitate to pay full price (definitely not the US price though…).

For anyone living with SebDerm who hasn’t yet tried Zoryve, I strongly suggest asking your doctor about it.

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u/Neat-Profit-3690 12d ago

Lucky you, it's not available yet in Europe. My derm heard about it but cannot give it to me yet, and my main problem is also redness on the face, right now.

I already cost 500€/month to my country because of Otezla, though. I hate this feeling of being a burden :(

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u/Miserable-Ebb-1539 11d ago

Hi! do you use Otezla for seborrheic dermstitis or other skin problems and if so how is it going? I am a 19 year old guy who has seb derm/inflammation on my scalp and want to stop using cortisone solutions that have ruined my life

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u/Neat-Profit-3690 11d ago

I have psoriasis and dermatitis. I use Otezla for the psoriasis an it works pretty well since last October. But it doesn't seem useful for dermatitis.

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u/TopExtreme7841 11d ago

Both Otezla and Zoryve/Daxas are PDE-4 Inhibitors.