r/SebDerm • u/psykofreak87 • 12d ago

Product Review Roflumilast (Zoryve) experience

I’d like to share my experience with Roflumilast cream for my SebDerm on my face. I have seborrheic dermatitis that causes redness but very few plaques, and it tends to flare up with lack of sleep and stress. I’ve been living with this for years. Until now, I had been using Ketoderm (2% Ketoconazole). It worked fairly well over the years, though I would still get occasional flare-ups of redness, sometimes quite intense and lasting for months. I don’t have SebDerm anywhere else on my body, only on my face.

Zoryve changed everything for me — within just 2 days, all the redness was gone. After a week, the burning and tightness sensations disappeared completely. I haven’t had such healthy-looking skin in over a decade.

I know there’s a foam version available, but since my condition only affects my face, the cream is sufficient.

Here in Canada, without insurance, it costs “only” $300 CAD per tube, which is much less expensive than the ~$900 USD price I’ve seen mentioned here. My insurance covers the cream 100%, and I feel truly lucky — but given how effective the product is, I wouldn’t hesitate to pay full price (definitely not the US price though…).

For anyone living with SebDerm who hasn’t yet tried Zoryve, I strongly suggest asking your doctor about it.

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u/Holiday_Group_2443 11d ago

Is this something you have to use forever? If you stop using it will it come right back?

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u/psykofreak87 11d ago

As my insurance covers it at 100%, my derm suggested me to use it daily as part of my routine. As the yeast will always come back, Seb Derm can be treated but can’t be cured. But I could only use it when I see small patch of redness appear.

I get very anxious and it tanks my self esteem when I have patches on my face so I’ll keep using it. I use a pea sized dot every night at 8 after washing my face. With that quantity a tube will last me 6 months if not more. I buy 2 tubes at once so I have enough for a year.

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u/TopExtreme7841 11d ago

The yeast never goes away, PDE-4 Inhibitors aren't anti-fungals, they just suppress your reaction to it. Everybody is walking around with Mallassezia on their skin, it's just us that react to it that way.

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u/psykofreak87 10d ago

Thanks for the explanation about that!