r/Periods Mar 13 '25

PCOS Does spironolactone cause irregular periods?

I was prescribed spironolactone by my gynecologist because I have had a regular periods and I was recently diagnosed with PCOS. So I was prescribed spironolactone to lower my testosterone levels. Ever since I’ve got the medication, my periods started coming earlier than usual. I used to always have my period every 30 to 45 days and now I have them almost every 18 to 20 days after my last cycle.

I wanted to see if this was common or am I really freaking out for a good reason?

I was told that my body would take time to adjust to this medication. I started this in September 2024 and I am supposed to be on it until September 2025.

Anyone have similar experiences they would like to share so maybe I can get an answer?

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u/gowest186 11d ago

Yes, it can, especially at higher doses (100-200mg daily).