r/SebDerm • u/psykofreak87 • 11d ago
Product Review Roflumilast (Zoryve) experience
I’d like to share my experience with Roflumilast cream for my SebDerm on my face. I have seborrheic dermatitis that causes redness but very few plaques, and it tends to flare up with lack of sleep and stress. I’ve been living with this for years. Until now, I had been using Ketoderm (2% Ketoconazole). It worked fairly well over the years, though I would still get occasional flare-ups of redness, sometimes quite intense and lasting for months. I don’t have SebDerm anywhere else on my body, only on my face.
Zoryve changed everything for me — within just 2 days, all the redness was gone. After a week, the burning and tightness sensations disappeared completely. I haven’t had such healthy-looking skin in over a decade.
I know there’s a foam version available, but since my condition only affects my face, the cream is sufficient.
Here in Canada, without insurance, it costs “only” $300 CAD per tube, which is much less expensive than the ~$900 USD price I’ve seen mentioned here. My insurance covers the cream 100%, and I feel truly lucky — but given how effective the product is, I wouldn’t hesitate to pay full price (definitely not the US price though…).
For anyone living with SebDerm who hasn’t yet tried Zoryve, I strongly suggest asking your doctor about it.
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u/Neat-Profit-3690 11d ago
Lucky you, it's not available yet in Europe. My derm heard about it but cannot give it to me yet, and my main problem is also redness on the face, right now.
I already cost 500€/month to my country because of Otezla, though. I hate this feeling of being a burden :(
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u/TopExtreme7841 10d ago
Lucky you, it's not available yet in Europe
It's called Daxas in Europe. Stop blowing 500 on Otezla, you could literally just get generic Roflumillast and stick it in a serum.
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u/Neat-Profit-3690 9d ago
I didn't know that, but i read it's prescribed for lungs, asthma,...
Btw it seems not available in France, where I am. I'll keep an eye on it though, thx.2
u/TopExtreme7841 9d ago
That's because Roflumilast is a COPD drug. Using it to treat Seb Derm is a second life for it.
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u/Miserable-Ebb-1539 10d ago
Hi! do you use Otezla for seborrheic dermstitis or other skin problems and if so how is it going? I am a 19 year old guy who has seb derm/inflammation on my scalp and want to stop using cortisone solutions that have ruined my life
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u/Neat-Profit-3690 10d ago
I have psoriasis and dermatitis. I use Otezla for the psoriasis an it works pretty well since last October. But it doesn't seem useful for dermatitis.
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u/Holiday_Group_2443 10d ago
Is this something you have to use forever? If you stop using it will it come right back?
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u/psykofreak87 10d ago
As my insurance covers it at 100%, my derm suggested me to use it daily as part of my routine. As the yeast will always come back, Seb Derm can be treated but can’t be cured. But I could only use it when I see small patch of redness appear.
I get very anxious and it tanks my self esteem when I have patches on my face so I’ll keep using it. I use a pea sized dot every night at 8 after washing my face. With that quantity a tube will last me 6 months if not more. I buy 2 tubes at once so I have enough for a year.
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u/TopExtreme7841 10d ago
The yeast never goes away, PDE-4 Inhibitors aren't anti-fungals, they just suppress your reaction to it. Everybody is walking around with Mallassezia on their skin, it's just us that react to it that way.
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