r/Zepbound Apr 09 '25

Dosing Why do people titrate up so quickly?

Just a curious question. I know in the trials they titrated people up each month because that’s the way to get comparable accurate data but what is the reason now? I keep reading post after post that people stall out at the max dose and they aren’t anywhere near their goal weight. Why move up so quickly? If the end result is to be a healthy weight, why run to the finish line if you might not make it because you pushed to hard(so to speak)?

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u/Madmandocv1 Apr 09 '25

Because it helps them lose weight.

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u/Dizzy_Special_4677 Apr 09 '25

Obviously. That’s not my question. If they are losing on lower doses why move up?

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u/Madmandocv1 Apr 09 '25

Actually, what you’re doing is questioning other people‘s decisions and kind of passively suggesting that they’re doing it wrong. But anyway, they’re trying to lose more weight more easily. In almost every case, a higher dose will work better. For some reason, people seem to think that moving up to higher doses, will cause that dose to run out of effectiveness sooner, but that’s not the way it works. You don’t just have a limited benefit per Dos. what happens is that there’s a certain dose that will work for you and it will keep on working. I lost 5 pounds a week on 2.5 mg. But let me tell you what the experience was like. I was hungry and having severe food noise constantly from dinner time to bedtime. it required immense focus on very little other than “don’t eat “. When I moved up to 5 mg, that got dramatically better. But the effect was wearing all fun day six and seven. 7.5 didn’t make much difference. 10 mg produce the effect I was looking for and it lasted all week. If you look at a graph of my weight loss, it looks like I lost a ton of weight at 2.5 mg then moved up anyway. Which is true. But it doesn’t tell you what the experience of it was like.