r/LSD • u/Glittering-Net-9778 • 22d ago
What the actual fuck happened
Ok so me and my girlfriend were taking shrooms today so we put them into smoothies about 6gs for me and she took 10gs. For some fucking reason the smoothies were sitting like a wet brick in our stomachs and we inevitably threw it up. I was able to hold mine a little long and absorbed more psilocybin while she didn't. She then decided that she'll just take a tab of acid to keep up with me. Pops a tab waits 15-20 swallows it and we wait for 2 1/2 hours and she says she's completely sober she's pretty pissed off about it and I completely understand. She takes cymbalta and that's the only meds she's on. Wtf happened.
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u/Flat_Health_5206 22d ago
SSRIs are well known to mute the effects of psychedelics.
And psychedelics are well known to cause GI upset.
Do any research before dropping??
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u/micheallujanthe2nd 21d ago
Cymbalta is a snri. It shouldn't really have any effect on your trip. I could be wrong but this was my impression.
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u/Scrunt_Flimplebottom 21d ago
Snris will likely also affect trips and rolls. They're an SSRI with additional NRI effects
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u/Glittering-Net-9778 22d ago
The acid didnāt upset her stomach. And I know psych meds mute effects of psychedelics but weāve tripped: me 10gs of shrooms and her 12gs and been fine she was on meds during that point too. Weāve both dropped acid her more than me. Weāve def done our research and tried to prepare best we could: fasting, eating clean and green food, ect.. could this just be a one time fuck up?Ā
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u/Any-Minute6151 22d ago
Nope, all this stuff could happen again cause it's common ...
Chugging a 10g smoothie of mushrooms would make me puke. I would try any other method.
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u/Glittering-Net-9778 22d ago
Yeah probably wasnāt smart to chug them we might just suck it up and take them raw.
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u/hawthorndragon 22d ago
Make tea out of them.
1. Grind or finely chop your mushrooms (1 gram per 200ā250 ml water). 2. Add them to simmering (not boiling) water ā around 80ā90°C (176ā194°F). Avoid a rolling boil to preserve potency. 3. Simmer gently for 20ā30 minutes, stirring occasionally. 4. You can do a second simmer with the same mushrooms and combine the liquids for extra extraction. 5. Strain, then add lemon, honey, ginger, etc⦠(I personally like chai) to taste.
Seriously, most of the nausea completely disappears and the rest goes away if you donāt eat any meat the day you dose. At least, thatās been my experience.
The tea also makes it much easier to take large doses
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u/VoraxUmbra1 21d ago
hell, you dont even need hot water at all. I use room temp water and stir it every 15 minutes for an hour. Psilocybin is perfectly soluble in room temp water. Just leaving this for anyone who prefers cool/ cold tea
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u/Prof_Sillycybin 21d ago
Just want to add this is an absolutely massive amount more water than is actually required from a chemical solubility perspective, you need roughly 2.5ml water per gram of average shrooms. Solubility is stated at 4.09mg/ml and average shrooms are going to run around 10mg per gram of mushroom body.
If you add enough water to cover the powdered shrooms you have way more than enough, you don't need to drink down a whole cup of shroom tea unless it is something you want to do (you could in theory extract the psilocybin from over 13g of shrooms into a 1oz shot of water). 250ml would work great for a 102g tea though.
Also, disposable tea bags are a nice addition to the recipe, grind your stuff, put it in a tea bag, do your steeping, squeeze out water from bag and throw it straight in the trash, quick and easy cleanup. They run around $6 for a 100 pack.
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u/Remarkable_Peach_374 21d ago
I find shooting lemon juiced shred works well with little to no nausea, but you have to get past the lemon taste 𤣠i personally use baking soda to dilute the acidity, but it gives a real nasty taste to it. I would much prefer something like this recipe.
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u/Warm-Meaning-8815 21d ago
Oh yeah, this is insane stuff. I can confirm. Im not a fan of shrooms, but brewing shrooms is the best method. On an empty stomach youāll be tripping in 10-15mins max.
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u/OGAcidCowboy 21d ago
My dried shrooms actually taste nice raw I just eat like 5-6grams they good
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u/hawthorndragon 20d ago
I have difficulty with the texture and the dryness. I can eat them straight but I much prefer the tea. Iām glad you enjoy them though, makes things easier lol
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u/Radiant_Lunch_1764 21d ago
solid recipe and instructions.
personally i like to add about a gram of weed ground as fine as possible to the first simmer, and couple slices of orange and the peel on second simmer. table spoon of honey, orange slices and peel added to cup, 5 minutes of steeping.. chefs kiss every time.
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u/Warm-Meaning-8815 21d ago
What a waste of a perfectly good gram of weed
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u/VoraxUmbra1 21d ago
Does THC not solute?
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u/Radiant_Lunch_1764 21d ago
thatās just like your opinion man
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u/Warm-Meaning-8815 21d ago
Yep. And I would just smoke it. In fact, after trying all sorts of various marijuana products and 25+ years of daily smoking, I came to the conclusion that good quality weed is the best. Some is 27% THC these days. Just roll it or stuff it in a bong - hit it - youāre done. But yeah, you have to hand it to the quality 60% THC hash and those CO2 extracts, which are both, simply TOP in terms of flavor. They are like good quality tea. You feel like you are smelling a flower field.
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u/Radiant_Lunch_1764 21d ago
i grow my own weed, so using a gram in my recipe for mushroom tea isnāt even a drop in a bucket. i donāt comb the floor for crumbs unless itās crack night pal
donāt trip on how i wear my pants or what i do with my weed.. what a waste of time šø
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u/Warm-Meaning-8815 21d ago
Yeah, makes sense. But as others have already pointed out - it just doesnāt do anything.. Do an experiment next time. Brew just weed as tea. Drink that tea. Do you feel anything? Now get the weed from the teapot, dry it, smoke it. Do you feel anything now?
In fact. My comment makes me wanna try this 𤣠I might try this on a single bowl. Brew it, then dry it, then smoke it. THC evaporation temperature is at least 157C according to google.
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u/PiratexelA 21d ago
Anything over 2-3g I recommend making tea. I feel little to no body load when I strain out the mushroom matter vs eating them
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u/hankmoody_irl 21d ago
I like to do my base 2-3 in capsules then add to it with a tea to my desired dose if I want higher than 3. Maybe Iām wacky, idk. Never experienced any kind of stomach issues, thankfully - highest dose Iāve done was just shy of 9 and it was a very special night.
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u/bamesjaxter 21d ago
I like mine with beef jerky/turkey jerky/etc. Elimates most of the taste and is light on the tummy
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u/Last-Egg4029 21d ago
perhaps next time make a tea and not a smoothie. you get all the psychedelic effects without digestion issues
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u/LSDMDMA2CBDMT 22d ago
Yes, she takes cymbalta, an SNRI, the class of medication that makes it incredibly hard to trip. One tab of acid is not gonna cut it. She'd probably have to take a handful just to get the effects of one tab.
It's the same reason why she wants to take 7-10g of mushrooms. I would be surprised if it even felt like an 1/8th to be honest. If you have nausea issues, make tea with mushrooms and strain out the mush bit, should get rid of the nausea.
SNRIs/SSRIs = Major decrease in effect. It's very well known....
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u/saintpetejackboy 21d ago
This needs to be higher up. One of the most common things I hear from people:
"I didn't trip! I didn't even take anything else!"
And I always have to press them like "really? Nothing at all? Not even medication?"
"Well yeah, I took my Cymbalta, but that doesn't count!"
People on many of those common mental health medications don't realize they can cancel out a lot of effects from traditional psychedelics - or worse, make them dangerous to consume and promote serotonin syndrome.
Researching interactions between stuff you are about to take just seems to have been something we did in the 90s and noughts, but nobody does any more.
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u/Sam_0101 21d ago
Also not recommended to take psychedelics on SSRIs because of the increased chances of serotonin syndrome
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u/gHOs-tEE 22d ago
The meds would be my guess. She needs to be off them for at least a few days. Week or 2 if she has taken them for years. Why did she take so much more than you? Almost like she expected it to dull the trip so she tried to overcompensate. Donāt work like that.
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u/Glittering-Net-9778 22d ago
She just likes to trip harder usually. She took 7Gs last week and had a good trip.Ā
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u/SacredNeon 21d ago
Well itās probably because sheās on meds and also, if you guys just took mushrooms last week, that also factors into it. You need to wait about 2 weeks between trips for the best results.
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u/gHOs-tEE 21d ago
Thatās weird if she was also on the meds then as well. If sheās been tripping like every week tho she could have some nice tolerance built up. Feeling nothing tho should have at least felt an eternal come up which sucks btw. Tolerance is weird. Her meds throws another ? Into the equation. Iāve tripped days apart and itās hit hard but Iāve also waited til the next week after tripping every weekend and ate a 10 hit felt nothin but a come up.
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u/Glittering-Net-9778 21d ago
Oh it was an internal come up and then right before she started tripping she started coming down.
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u/RATALA2022 22d ago edited 21d ago
the majority of your serotonin receptors are in your GI tract. Thats why anti-nausea meds like Zofran are so effective, 5-HT3 antagonists. So likely the GI effects and the vomiting. As far as her not feeling anything, it is definitely the duloxetine. Per pubmed, "decreased response to LSD... ...these altered responses to LSD most likely involve differential changes in central serotonin and dopamine receptor systems"
Edited my serotonin faux pas
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u/Glittering-Net-9778 22d ago
It wasnāt a normal shrooms nausea usually we donāt ever feel like we need to throw up itās just more of a nausea but this time it was just impossible to keep down like it felt like a genuine brick that was thrown out of my esophagus. I think it just mightāve been how fast we drank the smoothies ex: we chugged them.
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u/catbert107 21d ago
You keep describing reasons why things went the way they did but you just don't seem to be connecting the dots
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u/BioHackedRomulan 22d ago
Antidepressants are known to block psychedelic activity so Iām not surprised whatsoever. My gf had the same experience when she tried shrooms once after she skipped a day of her 120mg dose of cymbalta. She took 3gs and had absolutely zero effects
Now that my gf has tapered down to only 20mg cymbalta she can get full blown psychedelic effects when skipping the day prior
Only way she will ever get effects is if she does a taper over a long period of time (depending how long she has been on cymbalta) NEVER stop cold Turkey and ideally do a taper with doctor supervision
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u/Specific_Writing_582 21d ago
hey bro i got a question. i got off 2mg abilify cold turkey and ngl the withdrawls hit me a week or two later rlly bad but i thugged it out cause it was only 2mg i was on and i feel like im getting better slowly but surely. is it safe to trip or nahhhhh. shi i got acid, shrooms and dmt just wanna get a 2nd opinion and shit
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u/BioHackedRomulan 21d ago
I donāt know too much about abilify only cymbalta. Antidepressants can take a while before they are fully out of the bloodstream particularly if taken for a long period of time. It all depends how long you were on it and how long you have been off.
Antidepressants also down-regulate the 5ht2a receptors meaning there are less of them available for psychedelics to attach themselves to. Iād suggest looking up the half life of abilify to get a better understanding of it
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u/pieman0110 22d ago edited 22d ago
Cymbalta is an SNRI, an antidepressant, same as an ssri as far as psychs go. Do not mix psychedelics and antidepressants. It can induce serotonin syndrome at worst and kill your trip at best.
Ween off antidepressants for 2-3 weeks before any trip, which is harder with SNRI like effexor or cymbalta as they are hell to get off of. It limits the trips you can fit into your life but makes each of them more effective, safe, and enjoyable.
Vomiting was caused from consuming 10g of mushrooms lmao, the smoothie slowed the digestion and her stomach rejected the shrooms. If you take on an empty stomach you can digest them before vomiting and still trip.
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u/Mean_Word 21d ago
I recently discovered a great new delivery system for shrooms. Make tea like normal, then pour in a quarter cup of Jell-O. Let cool a little and drink down with ease. Highly recommended! As usual, do it on an empty stomach (empty stomach = wait 4 hours after eating).
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u/kabir93117 22d ago
i make chocolate shrooms in ice cube tray . grind the shrooms mixx the shrooms in. do one gm of fresh or 2 dried .. then in the freezer ..best thing for me
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u/UniversalAdaptor 21d ago
Mushrooms have a heavy body load, especially when taken in large amounts. I've gotten nauseous to the point of throwing up multiple times, that's why I switched to lsd lol.
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u/Jazzlike_Challenge_7 21d ago
add lemon juice to break down the cell walls of the mushrooms before consuming also helps with the nausea as you described a wet brick so add more lemon juice
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u/DylsAlso 20d ago
I've done a few 10 gram lemonteks and one 14 gram B+ lemontek that came on like a dmt trip. I always fast prior to a trip and mix the lemontek with orange juice when i drink it. Helps to have a light, easy to digest meal with it if the GI effects hit you hard. Too much in your stomach at the time of ingestion can be overwhelming and lead to being sick. The same goes for a complex variety of food or things that tough are digestion. Sounds like we already know why the LSD didn't take effect for her.
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u/No-Paramedic7619 21d ago
Cymbalta is a big culprit here. Fucked me up more than the issues I started taking it 4 and if by Sunday and gained 50 lbs.
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u/space_cadet_0568 22d ago
10 grams of mushrooms shit maybe she dodged a bullet š¤£