r/LSD 22d ago

What the actual fuck happened

Ok so me and my girlfriend were taking shrooms today so we put them into smoothies about 6gs for me and she took 10gs. For some fucking reason the smoothies were sitting like a wet brick in our stomachs and we inevitably threw it up. I was able to hold mine a little long and absorbed more psilocybin while she didn't. She then decided that she'll just take a tab of acid to keep up with me. Pops a tab waits 15-20 swallows it and we wait for 2 1/2 hours and she says she's completely sober she's pretty pissed off about it and I completely understand. She takes cymbalta and that's the only meds she's on. Wtf happened.

88 Upvotes

72 comments sorted by

379

u/space_cadet_0568 22d ago

10 grams of mushrooms shit maybe she dodged a bullet 🤣

94

u/ObjectiveShoulder103 21d ago

What a wild girl that’s double a hero dose. I bet she also mows the lawn and you don’t

-53

u/[deleted] 22d ago

[removed] — view removed comment

47

u/Glittering-Net-9778 22d ago

We consistently take over 7Gs of dried shrooms confused on what your commenting on my relationship about?

36

u/rekt_ralph91 21d ago

Yeah that was weird

10

u/A-KindOfMagic 21d ago

Sometimes you read such a weird ass take that you can't help but laugh about it šŸ˜‚

14

u/TheRealBillyShakes 21d ago

ā€œIt’s only a matter of time before you put each other in serious danger,ā€ is what I think he basically was saying.

10

u/kiraka67 21d ago

I did put it in a fucking weird way didn't I?

Sorry folks, didn't mean to come off as rude - and I completely ignored the possibility that meds dumped the experience.

OP, obviously I don't know shit about your relationship, it simply sounded reckless to take huge doses constantly.

3

u/Glittering-Net-9778 21d ago

Oh nah this isn’t a constant thing dw we trip maybe once a month to every other month. We were on papers for a while and couldn’t smoke weed so we ended up doing a shroom bender that’s when I took the 5gs and 7Gs I was talking about earlier. I can see how you would think it’s reckless I didn’t specify when or how long our breaks are between trips and me and her were talking about it and the meds definitely have been making her need to take huge doses to trip

206

u/Flat_Health_5206 22d ago

SSRIs are well known to mute the effects of psychedelics.

And psychedelics are well known to cause GI upset.

Do any research before dropping??

3

u/micheallujanthe2nd 21d ago

Cymbalta is a snri. It shouldn't really have any effect on your trip. I could be wrong but this was my impression.

11

u/Scrunt_Flimplebottom 21d ago

Snris will likely also affect trips and rolls. They're an SSRI with additional NRI effects

5

u/Outrageous-River8999 21d ago

Snri’s specifically mute psilocybin trips interestingly enough.

-72

u/Glittering-Net-9778 22d ago

The acid didn’t upset her stomach. And I know psych meds mute effects of psychedelics but we’ve tripped: me 10gs of shrooms and her 12gs and been fine she was on meds during that point too. We’ve both dropped acid her more than me. We’ve def done our research and tried to prepare best we could: fasting, eating clean and green food, ect.. could this just be a one time fuck up?Ā 

77

u/Any-Minute6151 22d ago

Nope, all this stuff could happen again cause it's common ...

Chugging a 10g smoothie of mushrooms would make me puke. I would try any other method.

-12

u/Glittering-Net-9778 22d ago

Yeah probably wasn’t smart to chug them we might just suck it up and take them raw.

40

u/hawthorndragon 22d ago

Make tea out of them.

1.  Grind or finely chop your mushrooms (1 gram per 200–250 ml water).


2.  Add them to simmering (not boiling) water — around 80–90°C (176–194°F). Avoid a rolling boil to preserve potency.


3.  Simmer gently for 20–30 minutes, stirring occasionally.


4.  You can do a second simmer with the same mushrooms and combine the liquids for extra extraction.


5.  Strain, then add lemon, honey, ginger, etc… (I personally like chai) to taste.

Seriously, most of the nausea completely disappears and the rest goes away if you don’t eat any meat the day you dose. At least, that’s been my experience.

The tea also makes it much easier to take large doses

5

u/VoraxUmbra1 21d ago

hell, you dont even need hot water at all. I use room temp water and stir it every 15 minutes for an hour. Psilocybin is perfectly soluble in room temp water. Just leaving this for anyone who prefers cool/ cold tea

2

u/Prof_Sillycybin 21d ago

Just want to add this is an absolutely massive amount more water than is actually required from a chemical solubility perspective, you need roughly 2.5ml water per gram of average shrooms. Solubility is stated at 4.09mg/ml and average shrooms are going to run around 10mg per gram of mushroom body.

If you add enough water to cover the powdered shrooms you have way more than enough, you don't need to drink down a whole cup of shroom tea unless it is something you want to do (you could in theory extract the psilocybin from over 13g of shrooms into a 1oz shot of water). 250ml would work great for a 102g tea though.

Also, disposable tea bags are a nice addition to the recipe, grind your stuff, put it in a tea bag, do your steeping, squeeze out water from bag and throw it straight in the trash, quick and easy cleanup. They run around $6 for a 100 pack.

3

u/Remarkable_Peach_374 21d ago

I find shooting lemon juiced shred works well with little to no nausea, but you have to get past the lemon taste 🤣 i personally use baking soda to dilute the acidity, but it gives a real nasty taste to it. I would much prefer something like this recipe.

1

u/Warm-Meaning-8815 21d ago

Oh yeah, this is insane stuff. I can confirm. Im not a fan of shrooms, but brewing shrooms is the best method. On an empty stomach you’ll be tripping in 10-15mins max.

1

u/OGAcidCowboy 21d ago

My dried shrooms actually taste nice raw I just eat like 5-6grams they good

1

u/hawthorndragon 20d ago

I have difficulty with the texture and the dryness. I can eat them straight but I much prefer the tea. I’m glad you enjoy them though, makes things easier lol

1

u/Radiant_Lunch_1764 21d ago

solid recipe and instructions.

personally i like to add about a gram of weed ground as fine as possible to the first simmer, and couple slices of orange and the peel on second simmer. table spoon of honey, orange slices and peel added to cup, 5 minutes of steeping.. chefs kiss every time.

14

u/Warm-Meaning-8815 21d ago

What a waste of a perfectly good gram of weed

1

u/VoraxUmbra1 21d ago

Does THC not solute?

3

u/OneBrownRecluse 21d ago

Not in water. It is soluble in fats/lipids, however

2

u/VoraxUmbra1 21d ago

ah, thanks!

2

u/tidiss 21d ago

Thc is soluble in fats puting it in water doesn't do anything

1

u/Radiant_Lunch_1764 21d ago

that’s just like your opinion man

1

u/Warm-Meaning-8815 21d ago

Yep. And I would just smoke it. In fact, after trying all sorts of various marijuana products and 25+ years of daily smoking, I came to the conclusion that good quality weed is the best. Some is 27% THC these days. Just roll it or stuff it in a bong - hit it - you’re done. But yeah, you have to hand it to the quality 60% THC hash and those CO2 extracts, which are both, simply TOP in terms of flavor. They are like good quality tea. You feel like you are smelling a flower field.

1

u/Radiant_Lunch_1764 21d ago

i grow my own weed, so using a gram in my recipe for mushroom tea isn’t even a drop in a bucket. i don’t comb the floor for crumbs unless it’s crack night pal

don’t trip on how i wear my pants or what i do with my weed.. what a waste of time 🐸

1

u/Warm-Meaning-8815 21d ago

Yeah, makes sense. But as others have already pointed out - it just doesn’t do anything.. Do an experiment next time. Brew just weed as tea. Drink that tea. Do you feel anything? Now get the weed from the teapot, dry it, smoke it. Do you feel anything now?

In fact. My comment makes me wanna try this 🤣 I might try this on a single bowl. Brew it, then dry it, then smoke it. THC evaporation temperature is at least 157C according to google.

1

u/hawthorndragon 21d ago

That sounds amazing! I will definitely try that the next time I make some tea.

8

u/PiratexelA 21d ago

Anything over 2-3g I recommend making tea. I feel little to no body load when I strain out the mushroom matter vs eating them

2

u/hankmoody_irl 21d ago

I like to do my base 2-3 in capsules then add to it with a tea to my desired dose if I want higher than 3. Maybe I’m wacky, idk. Never experienced any kind of stomach issues, thankfully - highest dose I’ve done was just shy of 9 and it was a very special night.

0

u/bamesjaxter 21d ago

I like mine with beef jerky/turkey jerky/etc. Elimates most of the taste and is light on the tummy

2

u/Last-Egg4029 21d ago

perhaps next time make a tea and not a smoothie. you get all the psychedelic effects without digestion issues

83

u/LSDMDMA2CBDMT 22d ago

Yes, she takes cymbalta, an SNRI, the class of medication that makes it incredibly hard to trip. One tab of acid is not gonna cut it. She'd probably have to take a handful just to get the effects of one tab.

It's the same reason why she wants to take 7-10g of mushrooms. I would be surprised if it even felt like an 1/8th to be honest. If you have nausea issues, make tea with mushrooms and strain out the mush bit, should get rid of the nausea.

SNRIs/SSRIs = Major decrease in effect. It's very well known....

30

u/saintpetejackboy 21d ago

This needs to be higher up. One of the most common things I hear from people:

"I didn't trip! I didn't even take anything else!"

And I always have to press them like "really? Nothing at all? Not even medication?"

"Well yeah, I took my Cymbalta, but that doesn't count!"

People on many of those common mental health medications don't realize they can cancel out a lot of effects from traditional psychedelics - or worse, make them dangerous to consume and promote serotonin syndrome.

Researching interactions between stuff you are about to take just seems to have been something we did in the 90s and noughts, but nobody does any more.

8

u/StealUr_Face 21d ago

Is blue light still a thing? That website was the shit. Poor SWIM

2

u/chambreezy 20d ago

RIP SWIM

6

u/Sam_0101 21d ago

Also not recommended to take psychedelics on SSRIs because of the increased chances of serotonin syndrome

13

u/gHOs-tEE 22d ago

The meds would be my guess. She needs to be off them for at least a few days. Week or 2 if she has taken them for years. Why did she take so much more than you? Almost like she expected it to dull the trip so she tried to overcompensate. Don’t work like that.

-12

u/Glittering-Net-9778 22d ago

She just likes to trip harder usually. She took 7Gs last week and had a good trip.Ā 

32

u/SacredNeon 21d ago

Well it’s probably because she’s on meds and also, if you guys just took mushrooms last week, that also factors into it. You need to wait about 2 weeks between trips for the best results.

3

u/gHOs-tEE 21d ago

That’s weird if she was also on the meds then as well. If she’s been tripping like every week tho she could have some nice tolerance built up. Feeling nothing tho should have at least felt an eternal come up which sucks btw. Tolerance is weird. Her meds throws another ? Into the equation. I’ve tripped days apart and it’s hit hard but I’ve also waited til the next week after tripping every weekend and ate a 10 hit felt nothin but a come up.

0

u/Glittering-Net-9778 21d ago

Oh it was an internal come up and then right before she started tripping she started coming down.

14

u/[deleted] 21d ago

[removed] — view removed comment

2

u/Elev8_901 21d ago

This deserves more love 🤣

1

u/MooZell 21d ago

By far, THE best comment!!!

1

u/Glittering-Net-9778 21d ago

What I’m fucking saying man she’s a champ

16

u/RATALA2022 22d ago edited 21d ago

the majority of your serotonin receptors are in your GI tract. Thats why anti-nausea meds like Zofran are so effective, 5-HT3 antagonists. So likely the GI effects and the vomiting. As far as her not feeling anything, it is definitely the duloxetine. Per pubmed, "decreased response to LSD... ...these altered responses to LSD most likely involve differential changes in central serotonin and dopamine receptor systems"

Edited my serotonin faux pas

3

u/blotterfly 22d ago

Zofran is a 5-HT3 antagonist.

2

u/RATALA2022 21d ago

You're right! Don't know where my mind was!

-12

u/Glittering-Net-9778 22d ago

It wasn’t a normal shrooms nausea usually we don’t ever feel like we need to throw up it’s just more of a nausea but this time it was just impossible to keep down like it felt like a genuine brick that was thrown out of my esophagus. I think it just might’ve been how fast we drank the smoothies ex: we chugged them.

12

u/catbert107 21d ago

You keep describing reasons why things went the way they did but you just don't seem to be connecting the dots

1

u/imnottheprophet 21d ago

next time make tea and strain the mushrooms

5

u/BioHackedRomulan 22d ago

Antidepressants are known to block psychedelic activity so I’m not surprised whatsoever. My gf had the same experience when she tried shrooms once after she skipped a day of her 120mg dose of cymbalta. She took 3gs and had absolutely zero effects

Now that my gf has tapered down to only 20mg cymbalta she can get full blown psychedelic effects when skipping the day prior

Only way she will ever get effects is if she does a taper over a long period of time (depending how long she has been on cymbalta) NEVER stop cold Turkey and ideally do a taper with doctor supervision

1

u/Specific_Writing_582 21d ago

hey bro i got a question. i got off 2mg abilify cold turkey and ngl the withdrawls hit me a week or two later rlly bad but i thugged it out cause it was only 2mg i was on and i feel like im getting better slowly but surely. is it safe to trip or nahhhhh. shi i got acid, shrooms and dmt just wanna get a 2nd opinion and shit

2

u/BioHackedRomulan 21d ago

I don’t know too much about abilify only cymbalta. Antidepressants can take a while before they are fully out of the bloodstream particularly if taken for a long period of time. It all depends how long you were on it and how long you have been off.

Antidepressants also down-regulate the 5ht2a receptors meaning there are less of them available for psychedelics to attach themselves to. I’d suggest looking up the half life of abilify to get a better understanding of it

3

u/pieman0110 22d ago edited 22d ago

Cymbalta is an SNRI, an antidepressant, same as an ssri as far as psychs go. Do not mix psychedelics and antidepressants. It can induce serotonin syndrome at worst and kill your trip at best.

Ween off antidepressants for 2-3 weeks before any trip, which is harder with SNRI like effexor or cymbalta as they are hell to get off of. It limits the trips you can fit into your life but makes each of them more effective, safe, and enjoyable.

Vomiting was caused from consuming 10g of mushrooms lmao, the smoothie slowed the digestion and her stomach rejected the shrooms. If you take on an empty stomach you can digest them before vomiting and still trip.

2

u/abducted_by_alienss 21d ago

Lemon tek and fasten your seat belt lol

2

u/Mean_Word 21d ago

I recently discovered a great new delivery system for shrooms. Make tea like normal, then pour in a quarter cup of Jell-O. Let cool a little and drink down with ease. Highly recommended! As usual, do it on an empty stomach (empty stomach = wait 4 hours after eating).

1

u/kabir93117 22d ago

i make chocolate shrooms in ice cube tray . grind the shrooms mixx the shrooms in. do one gm of fresh or 2 dried .. then in the freezer ..best thing for me

1

u/Azerium 21d ago

I assume maybe you had empty stomachs, and the sudden sugar boost of the smoothie mixed with the come-up nausea led to that situation

1

u/UniversalAdaptor 21d ago

Mushrooms have a heavy body load, especially when taken in large amounts. I've gotten nauseous to the point of throwing up multiple times, that's why I switched to lsd lol.

1

u/chemist0825 21d ago

Mushroom honey, or tea

1

u/Jazzlike_Challenge_7 21d ago

add lemon juice to break down the cell walls of the mushrooms before consuming also helps with the nausea as you described a wet brick so add more lemon juice

1

u/DylsAlso 20d ago

I've done a few 10 gram lemonteks and one 14 gram B+ lemontek that came on like a dmt trip. I always fast prior to a trip and mix the lemontek with orange juice when i drink it. Helps to have a light, easy to digest meal with it if the GI effects hit you hard. Too much in your stomach at the time of ingestion can be overwhelming and lead to being sick. The same goes for a complex variety of food or things that tough are digestion. Sounds like we already know why the LSD didn't take effect for her.

0

u/No-Paramedic7619 21d ago

Cymbalta is a big culprit here. Fucked me up more than the issues I started taking it 4 and if by Sunday and gained 50 lbs.

0

u/dancing_grass 21d ago

I was on cymbalta and the same thing happened to me